Pathological changes in the Salience Network in schizophrenia.
30 Aug 2022
Psychiatry
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C9orf72-Associated Frontotemporal Dementia And Psychosis
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Frontotemporal dementia (FTD) is a progressive neurodegenerative disease. About 30-40% of the cases have a positive family history, and...
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ESRS Sleep Medicine Textbook
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Mania With Depressive Symptoms: A Pathophysio-Logical Review
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Contemporary Perspectives On Lacanian Theories Of Psychosis
05 Aug 2013
Jonathan D. Redmond* School of Counseling, Australian College of Applied Psychology, Melbourne, VIC, Australia In contemporary...
Study Identifies Predictors Of Cognitive Impairment In Schizophrenia
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A model using three patient characteristics was a significant predictor of general neurocognitive impairment in patients 3 years after...
Intervention For Epilepsy Patients Helped Prevent Depression
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A home-based intervention that incorporated components of mindfulness and cognitive-behavioral therapy led to the prevention of...
SSRI Antidepressants Safe For Depressed Epilepsy Patients
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Selective serotonin reuptake inhibitor and serotonin-norepinephrine reuptake inhibitor antidepressants did not increase seizure frequency...
Panel Votes Against Hydrocodone Because Of Abuse Potential
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The majority of a Food and Drug Administration advisory panel voted against approval of an extended-release, single-ingredient capsule...
DSM-5 Cleared For Takeoff
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In case you missed the big news, last weekend, the American Psychiatric Association’s Board of Trustees voted on and approved the final...
ICD Shocks Boost Anxiety And Mortality
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When patients receive shocks from implantable cardioverter defibrillators their anxiety level rises, and so does their mortality rate....
Attention Retraining Enhances CBT For Adolescent Anxiety
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Attention-retraining therapy works in adolescents with anxiety disorders, the first randomized, controlled trial in this age group has...
Family-Focused Therapy May Help Resistant Pediatric OCD
28 Nov 2012
An innovative family-focused treatment program for complex cases of pediatric obsessive-compulsive disorder that looked promising in a...
Using SSRIS In Pregnancy
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Over the last decade, attention in the medical literature has gathered logarithmically to focus on potentially efficacious treatments for...
Patients At Risk For Psychosis Show Gradual Decrease In Hippocampal Volume
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Patients with an at-risk mental state for psychosis gradually lost hippocampal volume as analyzed with MRI even though only about half of...
Marijuana Use Linked To Better Adherence In Psychosis
20 Nov 2012
First-episode psychosis patients who continue to use marijuana after beginning treatment are more likely to adhere to their medication...
Zolpidem Linked To Higher Inpatient Fall Rates
19 Nov 2012
Administration of zolpidem in hospital patients is associated with a significantly higher risk of falls according to a Mayo Clinic study...
RAISE: Early Intervention In Schizophrenia Put To The Test
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The National Institute of Mental Health is putting its research and clinical muscle into determining whether early intervention in...
Older Adults With Schizophrenia Can Achieve Remission
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Many older adults with a history of chronic schizophrenia can have a sustained remission if they receive appropriate psychosocial...
Marijuana Use Linked To Better Adherence In Psychosis
12 Nov 2012
First-episode psychosis patients who continue to use marijuana after beginning treatment are more likely to adhere to their medication...
Don’t Overreach For Subthreshold Pediatric Bipolar Disorder
06 Nov 2012
When youths get referred for help with symptoms that don’t quite meet diagnostic criteria for bipolar illness, there’s a 50-50 chance...
Liquid, Extended-Release Drug Approved For ADHD
04 Oct 2012
An extended-release liquid formulation of methylphenidate, taken once a day, has been approved by the Food and Drug Administration for...
Depression Can Be Migraine’s Tipping Point
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Depression in patients with episodic migraine is an independent risk factor for transformation of their headache pattern into far more...
Obstructive sleep apnea, oxidative stress and endotelial dysfunction
11 Sep 2012
F. Angelico, M. Del Ben, M. Fabiani, Department of Internal Medicine and Medical Specialities, Sapienza University, Rome, Italy...
More Evidence Confirms Relevance of Risk Allele to Schizophrenia
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The rs1344706 SNP on the ZNF804a gene was found to correlate with the volume of cortical white matter in schizophrenia patients and...
Insomnia Drug Helps Patients Sleep Sooner, Longer
03 Sep 2012
The promise of shorter time to sleep, longer sleep duration, and fewer side effects associated with the experimental sleep drug suvorexant...
CPAP Improves Mood in Sleep Apnea Patients
22 Aug 2012
BOSTON – Treatment with continuous positive airway pressure does double duty in patients with obstructive sleep apnea by improving their...
Watch for Heavy Smoking in Schizophrenia
22 Aug 2012
Patients with schizophrenia who are heavy cigarette smokers are more likely to use substances such as alcohol than are those with the...
Obesity and diabetes linked to cognitive decline
21 Aug 2012
People who are obese and have other metabolic abnormalities such as diabetes can experience a faster decline in their cognitive abilities,...
Hoarding Not Related To OCD, New Findings Reveal
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A report published in the August issue of Archives of General Psychiatry, a JAMA Network publication, has found that patients with...
Obesity Could Be Treated With Deep Brain Stimulation
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A review article in the August issue of Neurosurgery, the official journal of the Congress of Neurological Surgeons, suggests that...
Combination Therapy Yields Mixed Results for PTSD, Substance Abuse
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A program of cognitive-behavioral therapy combined with substance abuse treatment decreased the symptoms of posttraumatic stress disorder...
OCD Commonly Precedes Schizophrenia in Men With Both
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Symptoms of obsessive-compulsive disorder preceded symptoms of schizophrenia in 48% of 133 patients hospitalized over an 11-year period...
Depression May Shorten Survival in Kidney Cancer
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Depression does more than strike at the heart; it can compromise survival for patients with metastatic kidney cancer. Researchers from the...
Exercise Rivals Sertraline in Comorbid CHD, Depression
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Ninety minutes of aerobic exercise per week reduced depressive symptoms in patients with stable coronary heart disease to the same extent...
Suicidality Tied to ‘Self-Disorders’ in Early Schizophrenia
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Among patients having their first episode of schizophrenia, suicidality is clearly associated with an altered sense of self, or what some...
Tobacco, Drug Use High Early in Course of Schizophrenia
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Illicit drug use is common among heavy cigarette smokers in the general population, but among outpatients with schizophrenia who are heavy...
Lifetime Estrogen Exposure Linked to Depression Risk in Perimenopause
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Estrogen exposure across the lifespan appears to be associated with risk of depression during the menopausal transition, according to...
Intranasal Oxytocin May Ease Schizophrenia Symptoms
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Interest in the use of intranasal oxytocin for the treatment of psychiatric disorders has expanded in recent years, and several new...
Medical Comorbidity Affects Disease Course in Bipolar Disorder
27 Jun 2012
The burden of comorbid medical illness is high, and is linked to increased prescribing of psychotropic drugs, in patients with bipolar I...
Skimping on Sleep May Increase Stroke Risk
19 Jun 2012
Consistently short sleep duration not only leaves otherwise healthy individuals tired, it also increases their risk of developing stroke,...
Levomilnacipran SR Effective for Major Depressive Disorder
15 Jun 2012
A sustained-release formulation of the investigational drug levomilnacipran was found superior to placebo for improving depressive...
Oppositional Defiant Disorder Linked to Symptoms of Schizophrenia Spectrum Disorder
14 Jun 2012
Many children with oppositional defiant disorder but not autism nevertheless exhibit elevated symptoms of autism spectrum disorder as well...
Raloxifene Gains Ground as Adjunctive Schizophrenia Treatment
02 Jun 2012
The estrogen hypothesis of schizophrenia holds that estrogen has a protective, mitigating effect on schizophrenia in women, and that this...
Novel Antipsychotic Treats Acute Mania in Bipolar Disorder
02 Jun 2012
The novel atypical antipsychotic drug cariprazine is effective for the treatment of acute mania associated with bipolar I disorder,...
Depot Injection Boosts Antipsychotic Compliance in Schizophrenia
24 May 2012
Long-acting, injectable formulations of antipsychotic drugs significantly boosted treatment compliance in patients with schizophrenia in a...
Depression, Obesity Linked in Older Women but Not Older Men
23 May 2012
The odds of depression are significantly elevated for older, obese women and significantly decreased for older overweight men, a study of...
Onset Periods of Depression Linked to Different Dementias
19 May 2012
Recurrent depression from midlife through late life increases the risk of vascular dementia, suggesting a progressive etiologic...
Persistent Daytime Sleepiness Common Despite Effective CPAP
18 May 2012
Excessive daytime sleepiness in patients with obstructive sleep apnea remains a common and often debilitating problem, despite optimal use...
Computer Training Leads to Lasting Improvements in Schizophrenia
16 May 2012
Schizophrenia patients who underwent 80 hours of computerized training showed significant and sustained improvements in the ability to...
Schizophrenia With Panic Disorder May Be a Distinct Subtype
16 May 2012
Schizophrenia with comorbid panic disorder, also known as panic psychosis, appears to be a distinct subtype of schizophrenia, according to...
Range of Childhood Trauma Linked to Schizophrenia Risk
15 May 2012
People with schizophrenia are more likely to report having had a wide range of unhappy childhood experiences than are healthy, age-matched...
Metformin Resolves Amenorrhea in Antipsychotic-Treated Schizophrenia
10 May 2012
Treatment with metformin led to striking resolution of amenorrhea in women with schizophrenia treated with an antipsychotic drug, in a...
Phone Therapy for Depression Boosts Treatment Adherence
07 May 2012
Adults with major depression were significantly less likely to discontinue treatment when they received telephone-administered cognitive...
Substance Abuse ‘Under-appreciated’ Among Elderly Psychiatric Inpatients
04 May 2012
More than one in 10 admissions to an acute psychiatric inpatient geriatric psychiatry service was associated with an alcohol or drug use...
Is My Child ‘Bipolar’?
26 Apr 2012
We all understand that bipolar disorder is a mood disorder, characterized by periods of depression and mania, that many of us have seen in...
Findings Boost Causal Argument for Smoking, Depression
24 Apr 2012
Current heavy smokers have a more than threefold increased risk for major depression, compared to former heavy smokers. And while the link...
Insomnia, Hypersomnia Disorders Criteria Proposed for DSM-5
22 Apr 2012
Proposed DSM-5 criteria for sleep-wake disorders include dropping the DSM-IV’s “primary insomnia” diagnosis in favor of...
‘Mind-Pops’ More Common in Schizophrenia
17 Apr 2012
High-functioning patients with schizophrenia experienced “mind-pops” significantly more often than did two control groups in a...
Depression Linked to Unhealthy Dieting Among Women
14 Apr 2012
Women with depression engage in fewer healthy dieting behaviors such as eating fruits and vegetables, and more unhealthy dieting behaviors...
Cognitive Therapy Plus Active Monitoring Benefits People at Risk of Psychosis
12 Apr 2012
Cognitive therapy in help-seeking young people at risk for psychosis did not reduce the likelihood of transitioning to psychosis, but it...
Home Sleep Apnea Testing: Wake Up Call for Sleep Docs
13 Mar 2012
PHOENIX – Sleep medicine doctors need to get ahead of the curve on home sleep apnea testing or risk being put out of business, according...
Adjunctive Lithium Reduces Use of Newer Antipsychotics in Bipolar
06 Mar 2012
In a 6-month study, the use of adjunctive moderately dosed lithium to optimized treatment in patients with bipolar disorder was well...
FDA Approves First Generic Form of Escitalopram
05 Mar 2012
The first generic formulation of the selective serotonin reuptake inhibitor escitalopram has been approved by the Food and Drug...
Sleep-Disordered Breathing in Early Childhood Linked With Behavioral Outcomes
04 Mar 2012
Sleep-disordered breathing in infancy and early childhood increases the likelihood of problematic behavior in later childhood, findings...
Melatonin May Normalize Night Owl Sleep Schedules
14 Feb 2012
When patients’ sleep cycles are out of synch with the rest of the world, melatonin and light therapy can help. But for night owls – people...
Titrate ADHD Meds Quickly for Best Outcome
02 Feb 2012
A 15-day titration is usually the most economical and convenient way to identify the optimal dose of attention-deficit/hyperactivity...
School Staff Can Aid Treatment of Psychotic Children
25 Jan 2012
School staff can play an important role in helping children with psychotic disorders live more normal lives, according to Dr. Jonathan R....
FDA Approves Low-Dose Zolpidem for Night Awakening
24 Nov 2011
A low-dose sublingual formulation of zolpidem tartrate is the first agent to be approved to treat insomnia characterized by...
‘On-Off’ Switches Shed Light on Brain Disorders : Narcolepsy, cataplexy, and REM sleep behavior disorder linked to errant ‘flip-flop’ mechanisms.
14 Nov 2011
A series of “on-off” switches regulates sleep, clarifying many of the mechanisms underlying narcolepsy, cataplexy, and REM sleep behavior...