Treating Distal Aneurysms with the p48 LITE Flow Diverter: Early Experience from Klinikum Stuttgart

In this video, Prof. Hans Henkes and Dr. Ali Khanafer from the Department of Interventional Neuroradiology at Klinikum Stuttgart discuss their early clinical experience with the p48 LITE Flow Diverter from Wallaby Phenox for the treatment of distal intracranial aneurysms.

Distal aneurysms remain among the most technically challenging lesions to treat due to complex vascular anatomy and difficult distal access. Dr. Khanafer outlines how the p48 LITE, designed for delivery through a 0.017-inch microcatheter, may offer several advantages in these demanding cases, including improved navigability, reduced vessel straightening, lower friction during deployment, and enhanced procedural safety compared with larger microcatheter systems.

The discussion also highlights the benefits of the device’s Hydrophilic Polymer Coating (HPC) technology, which has enabled the Stuttgart team to routinely implant flow diverters and stents under single antiplatelet therapy protocols with favourable safety and efficacy outcomes.

Three illustrative cases are presented, including:

* A complex middle cerebral artery (MCA) bifurcation aneurysm with associated blister aneurysms
* An anterior communicating artery (AComA) aneurysm
* An isolated M2 segment aneurysm

For each case, the rationale behind treatment planning, device selection, and deployment strategy is reviewed, providing practical insights into the use of the p48 LITE in distal cerebrovascular interventions.

The clinicians conclude by sharing their initial impressions of the technology and discuss its potential role in expanding treatment options for patients with challenging distal aneurysms.

Special thanks to WallabyPhenox for supporting this video.