Treatment Options For Atypical Parkin-Sonisms

Author:D. V. Moretti

Volume Info:Volume 1 Issue 1

Volume 1 Issue 1 , pages 25-29
Published May 2015

D. V. Moretti
IRCCS S. Giovanni di Dio Fatebenefratelli, Brescia, Italy

Success in treating patients with atypical parkinsonisms remains exceedingly low. This finding probably relates to

the widespread distribution of the pathological changes that account for the varied and complex spectrum of clinical

manifestations. Dopaminergic drugs are regularly used for the parkinsonian features; however, these rarely result

in more than modest benefit. A variety of other treatments have been used in these disorders, sometimes directed

at other specific features such as dystonia or myoclonus, and these treatments will be reviewed. Greater success in

treating these disorders will require advances in our understanding of their cause(s) or the pathogenetic mechanisms

underlying the neurodegenerative processes. The similarities in the molecular pathology of these diseases suggest

that important advances in the management of one will have a definite impact on the treatment of the other.

atypical parkinsonisms, treatment options, pharmacological intervention, deep brain stimulation.

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