Abstract:

The Nucleus Accumbens is one of the basal ganglia and has been implicated of the pathophysiology of disorders such as depression and schizophrenia. It’s involvement in these disorders is fundamentally due to its role in the cortico-ganglia-thalamic loop. The Nucleus Accumbens receives dopaminergic inputs critically important in schizophrenia and is as key point of action of antipsychotic medication, yet it has very little research into neuropathological or functional changes. The research that does exist has produced directly contradicting results, with most of the repeatable findings coming from animal models of dopaminergic dysfunction

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