š§ Oruen CNS Weekly Roundup: The Latest in CNS Medicine š§ Ā
The CNS field continues to evolve rapidly, with new developments emerging across psychiatry, neurology, and interventional neuroscience. This weekās roundup highlights key updates across multiple therapeutic areas.
Oruen CNS Weekly Roundup: Latest Findings Across CNS Medicine
ADHD
ADHD brains may show āsleep-likeā activity while awake
Researchers identified brief sleep-like brain activity during waking tasks in people with ADHD, potentially explaining lapses in attention, slower responses and errors during cognitive demands.
Hyperlink:
https://www.sciencedaily.com/releases/2026/03/260317015928.htm
Depression
Perinatal depression peaks two weeks after childbirth
A large analysis published in The Lancet Psychiatry found that major depression in women and girls is most prevalent in the early postnatal period, with prevalence peaking around two weeks after birth.
Hyperlink:
https://medicalxpress.com/news/2026-05-major-depression-women-girls-peaks.html
Psychosis / Schizophrenia
Early social and academic struggles may precede psychosis risk
New findings from the AMP SCZ project suggest functional decline and negative symptoms can develop years before psychosis-risk syndromes are formally identified.
Hyperlink:
https://msutoday.msu.edu/news/2026/01/study-reveals-struggles-precede-psychosis-risk
Epilepsy
Zorevunersen shows promise in treatment-resistant Dravet syndrome
Early trial results suggest the investigational therapy zorevunersen may significantly reduce seizure burden in children with Dravet syndrome, a severe genetic epilepsy.
Headache / Migraine
Migraine with aura linked to higher ischemic stroke risk in older adults
A study published in Neurology found that migraine with aura was associated with increased ischemic stroke risk in middle-aged and older adults, while migraine without aura was not.
Hyperlink:
https://medicalxpress.com/news/2026-05-middle-aged-older-adults-migraine.html
Multiple Sclerosis
New MS research highlights findings from AAN 2026
A May 2026 MS research update summarises new data across treatment, symptoms, disease progression and quality-of-life outcomes presented at the AAN Annual Meeting.
Hyperlink:
https://mymsaa.org/news/whats-new-in-ms-research-may-2026/
Movement Disorders
Experimental LRRK2-targeting drug reduces Parkinsonās-linked protein
A first-in-human study reported that BIIB094, an experimental therapy targeting LRRK2, reduced levels of a Parkinsonās-linked protein by up to 60%.
Hyperlink:
https://medicalxpress.com/news/2026-04-experimental-drug-parkinson-linked-protein.html
Neuro-oncology
Glioblastoma may disrupt large-scale brain communication networks
A new study suggests glioblastoma survival is linked to how strongly the tumour affects white matter connectivity, reinforcing the view of glioblastoma as a network-level brain disease.
Hyperlink:
https://medicalxpress.com/news/2026-04-glioblastoma-impact-brain-prognosis.html